The program will consist of oral presentations and poster sessions. The poster board surface area is 100(H) x 85(W) cm.

29th May - Saturday

15.00 - 17.00 Registration
17.00 - 17.30 Welcome and Opening
Janez Plavec
Stanislav Pejovnik, Rector Magnificus, University of Ljubljana
Afternoon session in conjunction with WG2 of COST MP0802 (Chair: Joze Kobe)
17.30 - 18.00 Jyoti Chattopadhyaya
Some New Aspects of Conformationally-constrained Polynucleotides (DNA and RNA)
18.00 - 18.30 Zhen Xi, Zicai Liang
RNA Stability and RNAi Enhancement
18.30 - 19.00 Aaron E. Engelhart, Ozgul P. Cetinkol, Irena Mamajanov, Nicholas V. Hud
Thermodynamic and structural studies of ligand and solvent effects on the stability of various nucleic acid secondary structures
19.00 - 22.00 Poster session / Refreshments

30th May - Sunday

Morning session I (Chair: Jyoti Chattopadhyaya)
9.00 - 9.30 Vidhi Maheshwari, Patricia Marzilli, Luigi G. Marzilli
Conformations of the 17-membered Ptd(GpG) Macrocyclic Ring Formed by Pt Anticancer Drugs with DNA. Effect of Carrier Ligand Bulk, Including Model Having a Goldilocks-like Carrier Ligand
9.30 - 10.00 Giovanni Natile
Different processing of DNA adducts formed by platinum compounds with enantiomeric amine ligands
10.00 - 10.30 Naoki Sugimoto
Stabilization and Function of Nucleic Acids under Molecular Crowding Conditions
10.30 - 11.00 Coffeee Break
Morning session II (Chair: Piet Herdewijn)
11.00 - 11.30 Sarah C. Zimmermann, Joshua M. Sadler, Katherine Seley-Radtke
Exploring Structural Diversity in Nucleoside Drug Design
11.30 - 12.00 Mladen Mintas
The new pyrimidine, purine and 1,2,4-triazole derivatives of L-ascorbic acid: synthesis, cytostatic and antiviral activity potency evaluations
12.00 - 12.30 Silvana Raic-Malic
Non-natural nucleoside analogues for noninvasive monitoring of tumor cells using positron emission tomography (PET)
12.30 - 13.00 Joze Kobe
From Non-natural Bases and Nucleosides to their incorporation into ODNs forming Inter Molecular Quadruplexes
13.00 - 15.00 Lunch
Afternoon session I (Chair: Janez Mavri)
15.00 - 15.30 Jiri Sponer
Molecular Dynamics Simulations of Nucleic Acids
15.30 - 16.00 Modesto Orozco
Exploring DNA folding and unfolding from molecular dynamics simulations
16.00 - 16.30 Jelena Tamuliene, Mindaugas Leonas Balevicius
Electric Field Gradient of Several Modified Adenine-Thymine pairs. Ab initio study
16.30 - 17.00 Coffee Break
Afternoon session II (Chair: Mateus Webba da Silva)
17.00 - 17.30 Lea Spindler
G-wires from mononucleosides and short G-rich oligonucleotides
17.30 - 18.00 Alexandro Membrino, Luigi E. Xodo
Control of HRAS Transcription and Rationale Design of G4-Decoys for Cancer Therapy
18.00 - 18.30 Iztok Prislan, Jurij Lah, Matija Milanic, Gorazd Vesnaver
Folding and unfolding transitions of d(G4T4G3) in the presence of K+ ions
18.30 - 19.00 Kinga Majchrzak, Damian Smuga, Elzbieta Sochacka, Beata Kocon-Rebowska, Barbara Mikolajczyk, Barbara Nawrot
Deoxyribozyme 10-23 with extended catalytic properties
19.00 - 22.00 Dinner at hotel Sabotin

31st May - Monday

Morning session I in conjunction with WG2 of COST MP0802 (Chair: Lea Spindler)
9.00 - 9.30 Mateus Webba da Silva
Glycosidic Bond Angles to Understand and Control Folding of Nucleic Acid Quadruplexes
9.30 - 10.00 Aldo Galeone, Veronica Esposito, Antonella, Virgilio, Giuseppe Citarella, Alfonso Mangoni
Studies of heterochiral oligonucleotides forming quadruplex structures
10.00 - 10.30 Primoz Sket, Janez Plavec
Guanine-rich DNA sequences: Structures and cation interactions
10.30 - 11.00 Coffeee Break
Morning session II (Chair: Nicholas V. Hud)
11.00 - 11.30 Dorota Gudanis, Ryszard Kierzek, Zofia Gdaniec
Guanosine modification alters the strands orientation of the RNA tetraplex composed of trinucleotide CGG repeats
11.30 - 12.00 Gavin Collie, Stephen Neidle, Gary Parkinson, Shozeb Haider
A Crystallographic and Modeling Study of a Human Telomeric RNA (TERRA) Quadruplex
12.00 - 12.30 Sandro Cosconati, Luciana Marinelli, Roberta Trotta, Stefano De Tito, Bruno Pagano, Concetta Giancola, Luciano Mayol, Ettore Novellino, Antonio Randazzo
Structural and Conformational Requisites in DNA Quadruplex Groove Binding
12.30 - 13.00 Gavin Collie, Stephen Neidle, Silbia Sparapani, Gary Parkinson
First crystal structure of a telomeric RNA quadruplex-ligand complex shows a unique mode of ligand binding
13.00 - 15.00 Lunch
Afternoon session I (Chair: Antonio Randazzo)
15.00 - 15.30 Gyula Batta, Pal Herczegh, Delia Picone, Marta Bruix, Katalin E. Kover
NMR Methods to Disclose Structure and Dynamics of G4 Self Assemblies and RNases
15.30 - 16.00 Valerie Gabelica
Mass Spectrometry of G-quadruplexes
16.00 - 16.30 Il Joon Lee, Jeong Wu Yi, Byeang Hyean Kim
Nucleic Acid Sensing: Quencher-free Molecular Beacons (Qf-MB) and Fluorescent Oligonucleotide Probes
16.30 - 17.00 Coffee Break
Afternoon session II (Chair: Barbara Nawrot)
17.00 - 17.30 Dimitra Markovitsi
DNA fluorescence: from duplexes to quadruplexes
17.30 - 18.00 Piet Herdewijn
Towards a genetic enclave through the chemical modification of nucleotides and nucleic acids
18.00 - 18.30 Andreas Marx
Chemical Biology of DNA Replication
18.30 - 19.00 Leif A. Kirsebom, Shiying Wu, Stefan Trobro, Yu Chen
RNase P mediated catalysis - new insights
19.00 Dinner and visit to wine cellar

1st June - Tuesday