Trends in Biomolecular Structure
from Chemistry to Function

National Institute of Chemistry, Thurday, October 3

13.00-15.00 Registration and Refreshments
15.00-16.00 Welcome and opening
  Janez Plavec, head of Slovenian NMR Centre
  Franci Demšar, director, Slovenian Research Agency
  Carlo Rizzuto, president, Elettra Laboratory, Sincrotrone Trieste, Italy
  Matjaž Polak, director, EN-FIST Centre of Excellence, Slovenia
  Research at SLONMR
16.00-16.20 Primož Šket: Research of biologically important molecules at SLONMR: From small to large.
16.20-16.40 Simona Golič Grdadolnik: NMR assisted studies of non-covalent interactions: From protein folding to drug design
16.40-17.00 Gregor Mali: High-resolution solid-state NMR spectroscopy in Ljubljana: From catalysts and energy storage materials to pharmaceuticals
17.00-18.00 Official inauguration of the new 600 MHz NMR spectrometer
19.00 Dinner

Hotel Lev, Friday, October 4

  Morning session I
(Chair: Simona Golič Grdadolnik)
9.00-9.30 Robert Kaptein: Lac repressor-DNA interactions: Structure, dynamics allostery
9.30-10.00 Rolf Boelens: Structure and dynamics in gene regulation and DNA repair
10.00-10.30 Lucia Banci: NMR in cellular structural biology: From single molecules to pathways
10.30-11.00 Horst Kessler: The secret of Arachne: Structure and function of the folded C-and N-terminal domains of the spider silk protein by NMR spectroscopy
11.00-11.30 Posters and Coffee Break
  Morning session II
(Chair: Predrag Novak)
11.30-12.00 Zhen Xi: Quantitative structural insights into human Variegate Porphyria disease
12.00-12.30 Vladimír Sklenář: Ordering in disorder-Towards ultimate resolution in NMR studies of intrinsically disordered proteins
12.30-13.00 Kavita Dorai: Fluorine NMR and the 19F tensor: Useful probes of structure determination
13.00-14.30 Lunch
  Afternoon session I
(Chair: Vilko Smrečki)
14.30-15.00 Jyoti Chattopadhyaya: Can we control the phosphate degradation in nucleic acids by harnessing the relative hydration?
15.00-15.30 Naoki Sugimoto: How do non-canonical structures in template DNA affect transcription?
15.30-16.00 Mateus Webba da Silva: Programmed Quadruplex DNA folding
16.00-16.30 Posters and Coffee Break
  Afternoon session II
(Chair: Primož Šket)
16.30-17.00 Antonio Randazzo: Targeting G-quadruplexes, knowing G-triplex
17.00-17.30 Viktor Viglasky: Comparison of alternative structural motifs occurring in DNA: structure, function and biological impact
17.30-18.00 Rakesh N. Veedu: Novel nucleic acids for targeted therapy of solid tumors and Alzheimer’s disease
18.00-19.00 Poster Session
19.00 Closing remarks
  Conference dinner

Saturday, October 5

9.00 Networking activities, individual discussions, future collaboration planning
13.00 Lunch